Henrik Deber Dahlerup
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Methicillin Resistant S. aureus
Horizontal Gene Transfer
Expression of Genes
Cloning of Bacteria
Real Time QPCR
Real Time Reverse-Trancription-
Lactic Acid Bacteria
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An increasing and today impending problem for human health is bacterial resistance towards antimicrobial agents.
My key expertise is within the field of emergence, adaptation and spread of antimicrobial resistance in bacteria applying lab experiments and bioinformatics. My main focus is on Methicillin resistant Staphylococcus aureus (MRSA), and to a certain extent as well on multidrug resistance (MDR)-encoding E. coli and Salmonella. This expertise includes phenotypic and genotypic as well as bioinformatic methods to detect existing and new resistant determinants.
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Key Expertise 1
Time Tables 2
Former Time Tables 8
Former Lectures 9
Former Lab Calculations 10
Former Articles 11
Former Projects 12
1. ...This document describes a research regarding Methicillin Suspectable Staphylococcus aureus and Methicillin Resistance Coagulase Negative Staphylococcus in a biofilm, where there are investigated for horizontal transfer of the transposon SCCmec from Methicillin Resistance Coagulase Negative Staphylococcus to Methicillin Suspectable Staphylococcus aureus. This is conducted by detecting the gene mecA encoding the penicillinbinding protein PBP2a using a PCR assay. The research report describes a set of experiment observations which make the basis for a protocol mentioned below...
2. ...The goal of this review is therefore to compare widely different Methicillin resistant Staphylococcus aureus (MRSA) strains and the relevant Methicillin sensitive Staphylococcus aureus (MSSA) strain Newman as whole genomes, to reveal what there are present which potentially mediate toxin and/or fitness factor gene exchange in Methicillin resistant Staphylococcus aureus. Moreover, this review provides valuable speculations about locations on MRSA genomes which in the future potentially mediate toxin and/or fitness factor gene exchange...
3. ... This study contribute importantly with information associated with SCCmec excision regarding the two new S. aureus strains SO385 and EMRSA5096 and valuable speculations regarding regulation of the ccrA of strain N315.
4. ... The goal of this review is to examine genomic evidence for the evolutionary step from S. equi ssp. zooepidemicus to S. equi ssp. equi. It is likely that there have been loss, gain and regrouping of DNA sequences together with 'evolutionary bottlenecks' - one mediated by competition within the same subspecie, S. equi ssp. zooepidemicus.
5. ... It is presented in this study by PCR-Denaturing Gradient Gel Electrophoresis at the 16S rRNA gene in the V3 region, that the strains Lactobacillus plantarum, Leuconostoc mesenteroides and Lactobacillus brevis frequently appeared in the sourdoughs used in this study. Saccharomyces cerevisiae showed additionally, by the use of PCR-Denaturing Gradient Gel Electrophoresis at the 26S rRNA gene in the D1 region, that this yeast was in general present in the three different types of sourdough used in this study...
Materials 2011 - 2017
Materials 2005 - 2010
A Brief Description of Henrik Deber Dahlerup
During my whole childhood I lived in Fredericia (Denmark), where I attended a private school. Later I went to a college near by Ribe (Denmark).
A proactive history
Most of my youth was colored by a lot of exercise in the form of Taekwondo and later Jeet Kune Do and the most important part of the training is kept up until today. Back then, Jeet Kune Do was not present in Denmark, and I therefore participated in founding a nonprofessional club, where most of the training was located in Fredericiahallerne. Additionally to this work I graduated in courses at a gymnastics leader program at a college near by Ribe.
During college my interest in teaching was stimulated, which led to, that I joined a 3 year program with the specialty in advising about the nature (Denmark). Some of the program was situated in a nature center and here I had the opportunity independently to execute arrangements of direct nature advisement. Subsequently I was call-on worker to the nature center as a nature advisor (22 years old) in my spare time for a long period.
In 2001 I graduated as a labtechnician, where my greater project applied diagnostic techniques of bacteria. I followed an external program at the same time situated on the lab school (Denmark) in order to expand my IT skills, due to in general all analysis information is electronic managed at greater firms. At the end of my lab technician program I performed study relevant analysis work at a greater international firm.
In 2011 I graduated a Master Science degree in Biotechnology at the University of Copenhagen (Denmark) in the wish of achieving a greater comprehending level in the area of Microbial Biotechnology. During the second half of my Biotechnology study I worked at a genetic / Microbiology level with Lactic Acid Bacteria and Streptococcus equi and passed the course 'Project Management' with grace. In my M.Sc. thesis, also funded by Familielegatet, I worked with Methicillin Resistant Staphylococcus aureus (MRSA), where as an example cloning of bacteria and expression of genes was applied, and this has today been my documented focus for over 4 years.
I have as an example participated in projects the following places:
Current Articles, SOPs, Research Reports and Thesises:
Current Noncommercial Products:
I thank Familielegatet for funding my activities.
These home pages are religious, political and CO2-neutral.
©2017 Henrik Deber Dahlerup
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